Understanding bone cancer in dogs to improve treatments for humans
Official title: Clinical, molecular, and immune characterization of naturally occurring osteosarcoma in dogs
Funded at University of California at Davis · NIH-10890166 · Data updated 2026-11-12
This study is looking at how osteosarcoma, a type of bone cancer, affects dogs to learn more about the disease and improve treatments for both dogs and people with cancer.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California at Davis NIH-funded |
| Lab location | 1 site (Davis, United States) |
| Project start | August 1, 2023 |
| Project end | July 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $558,072 |
| NIH project number | 5U01CA281905-02 |
| Project ID | NIH-10890166 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are dogs diagnosed with naturally occurring osteosarcoma that are undergoing surgical treatment.
✕Less likely to help
Patients who do not have osteosarcoma or those who are not dogs will not benefit from this research.
What this research studies
This research investigates naturally occurring osteosarcoma in dogs, which can provide valuable insights into similar cancers in humans. By studying dogs with this disease, researchers aim to understand its progression and the immune response involved. The study will involve enrolling dogs that have been diagnosed with osteosarcoma and characterizing their tumors and immune environments. This approach may help refine treatment strategies for both dogs and humans suffering from this type of cancer.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment options and outcomes for patients with osteosarcoma.
How similar studies have gone: Previous research has shown that studying canine osteosarcoma can provide meaningful insights into human cancer treatment, indicating a promising avenue for further exploration.
Where this research is happening
-
University of California at Davis
Davis, United States Active
Researchers
- Principal investigator: Rebhun, Robert B — University of California at Davis
- Study coordinator: Rebhun, Robert B
Related research
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.