Understanding bone and muscle changes in COPD patients

: Osteoporosis and Sarcopenia in COPD and CT-based Phenotypes

NIH-funded research University of Iowa · NIH-11055630

This study is looking at how weak bones and muscles affect people with COPD by using special imaging and technology, and it aims to help doctors better understand and treat these issues in patients like you.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of Iowa NIH-funded
Lab location1 site (Iowa City, United States)
Project IDNIH-11055630 on NIH RePORTER

What this research studies

This research investigates how osteoporosis and sarcopenia affect patients with chronic obstructive pulmonary disease (COPD) by using advanced imaging techniques and artificial intelligence. The study will analyze data from large national lung studies to identify unique aging patterns in the bones and muscles of these patients. By examining chest CT scans, researchers aim to develop automated measures that can assess diaphragm function and other important features related to lung health. This approach could lead to better understanding and management of these conditions in COPD patients.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with chronic obstructive pulmonary disease (COPD) who may also be experiencing osteoporosis or sarcopenia.

Not a fit: Patients without COPD or those who do not have osteoporosis or sarcopenia may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could improve the diagnosis and treatment of osteoporosis and sarcopenia in COPD patients, leading to better health outcomes.

How similar studies have performed: Other research has shown promise in using imaging and AI to analyze lung conditions, suggesting that this approach could yield valuable insights.

Where this research is happening

Iowa City, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.