Understanding Body Clocks and Health with Advanced Data Tools
Bioinformatics Omic Platform for Circadian Biomedical Research
This project creates advanced computer tools to help scientists better understand how our body's natural rhythms, or circadian clocks, affect our health, including conditions like Alzheimer's disease.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California-Irvine NIH-funded |
| Lab location | 1 site (Irvine, United States) |
| Project ID | NIH-11142614 on NIH RePORTER |
What this research studies
Our bodies have natural 24-hour cycles, called circadian rhythms, that influence everything from sleep to metabolism and thinking. When these rhythms are disrupted, it can lead to various health problems, including those seen in Alzheimer's disease. This project is building specialized computer programs and databases to collect, organize, and analyze the vast amounts of molecular data related to these body clocks. By making sense of this complex information, we hope to uncover new ways that circadian rhythms impact health and disease.
Who could benefit from this research
Good fit: Patients with conditions linked to circadian rhythm disruptions, such as Alzheimer's disease, may ultimately benefit from the insights gained through this data analysis.
Not a fit: Patients whose health conditions are not related to or influenced by circadian rhythms may not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to a deeper understanding of how body clocks contribute to diseases, potentially guiding new strategies for prevention or treatment.
How similar studies have performed: While the development of these specific integrated informatics tools is novel, the importance of circadian rhythms in health and disease is well-established, with ongoing research in many areas.
Where this research is happening
Irvine, United States
- University of California-Irvine — Irvine, United States (Active)
Researchers
- Principal investigator: Baldi, Pierre — University of California-Irvine
- Study coordinator: Baldi, Pierre
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.