Understanding Body Changes from Exercise
Mayo Clinic Physical Activity Research Center: Metabolomics and Proteomics Analysis Site
This project looks at how exercise changes tiny particles and chemicals in the blood of both active and less active people.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project ID | NIH-11163547 on NIH RePORTER |
What this research studies
This project aims to understand how exercise, both short-term and long-term, affects the body at a molecular level. Researchers at Mayo Clinic are analyzing blood samples to find changes in small particles called exosomes and various chemicals (metabolites) after different types of exercise. They are comparing these changes between people who are very active and those who are sedentary. This work involves looking at how the body responds to single exercise sessions and to several months of regular aerobic and resistance training.
Who could benefit from this research
Good fit: People who are either very active or sedentary and willing to provide blood samples and participate in exercise training might be ideal candidates.
Not a fit: Patients not interested in physical activity or providing biological samples may not directly benefit from this specific research.
Why it matters
Potential benefit: This could help us understand how exercise improves health and potentially lead to new ways to measure fitness or personalize exercise plans.
How similar studies have performed: While the specific exosome methodology is innovative, the general approach of studying exercise's molecular effects has been explored in other contexts.
Where this research is happening
Rochester, United States
- Mayo Clinic Rochester — Rochester, United States (Active)
Researchers
- Principal investigator: Nair, K Sreekumaran — Mayo Clinic Rochester
- Study coordinator: Nair, K Sreekumaran
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.