NIH-funded research U01 cooperative agreement

Understanding blood sugar levels during pregnancy and their effects on mothers and children

Official title: Comparing Glycemic Profiles in Pregnancy and Maternal and Child Health Outcomes

Funded at Women and Infants Hospital-Rhode Island · NIH-10919226 · Data updated 2026-11-12

This study is looking at how blood sugar levels during pregnancy can impact the health of both moms and their babies, especially in relation to childhood obesity, and it's for pregnant women who are being tested for gestational diabetes.

More Pregnancy research and trials

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionWomen and Infants Hospital-Rhode Island
NIH-funded
Lab location1 site (Providence, United States)
Project startSeptember 20, 2019
Project endJuly 31, 2025
Funding year2024
Award (this year)$712,315
NIH project number5U01DK123783-05
Project IDNIH-10919226 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are pregnant women undergoing glucose tolerance testing, particularly those at risk for gestational diabetes.

Less likely to help

Patients who are not pregnant or those who do not undergo glucose tolerance testing may not benefit from this research.

What this research studies

This research investigates how blood sugar levels during pregnancy affect both maternal and child health outcomes. It focuses on women who undergo glucose tolerance tests to identify gestational diabetes and aims to understand the relationship between maternal glycemic profiles and the risk of childhood obesity in their offspring. By enrolling at least 400 pregnant women, the study will analyze the timing and types of blood sugar irregularities that may lead to complications. The goal is to break the cycle of gestational diabetes and obesity in future generations through improved understanding and treatment.

Why it matters

Potential benefit: If successful, this research could lead to better management of gestational diabetes, reducing the risk of obesity in children born to affected mothers.

How similar studies have gone: Previous research has shown that understanding maternal glycemic profiles can lead to improved health outcomes, indicating that this approach has potential for success.

Where this research is happening

  • Women and Infants Hospital-Rhode Island
    Providence, United States
    Active

Researchers

  • Principal investigator: Werner, Erika F — Women and Infants Hospital-Rhode Island
  • Study coordinator: Werner, Erika F

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.