Understanding blood flow issues in diabetic heart disease
Official title: Insights into Coronary Microvascular Dysfunction in Diabetic Cardiomyopathy
Funded at University of Arizona · NIH-11172152 · Data updated 2026-11-12
This study looks at how diabetes can cause problems with the small blood vessels in the heart, which affects blood flow and heart health, and it aims to find new treatments that could help improve heart function for people with diabetes.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Arizona NIH-funded |
| Lab location | 1 site (Tucson, United States) |
| Project start | September 1, 2023 |
| Project end | August 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $601,812 |
| NIH project number | 7R01HL165207-02 |
| Project ID | NIH-11172152 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults with diabetes who are experiencing heart-related issues.
✕Less likely to help
Patients without diabetes or those with obstructive coronary artery disease may not benefit from this research.
What this research studies
This research investigates how diabetes affects the small blood vessels in the heart, leading to problems with blood flow and heart function. It focuses on the mechanisms behind impaired blood vessel relaxation in diabetic patients, particularly how certain molecules like nitric oxide and hydrogen peroxide play a role. By studying these processes in both healthy and diabetic models, the research aims to identify potential treatments that could restore normal blood flow in the heart. Patients may benefit from insights that could lead to new therapies for heart issues related to diabetes.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that improve heart function and blood flow in diabetic patients.
How similar studies have gone: Previous research has shown promising results in understanding blood flow issues related to diabetes, making this approach both relevant and potentially impactful.
Where this research is happening
-
University of Arizona
Tucson, United States Active
Researchers
- Principal investigator: Yin, Liya — University of Arizona
- Study coordinator: Yin, Liya
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.