Understanding blood flow issues in diabetic heart disease
Insights into Coronary Microvascular Dysfunction in Diabetic Cardiomyopathy
This study looks at how diabetes can cause problems with the small blood vessels in the heart, which affects blood flow and heart health, and it aims to find new treatments that could help improve heart function for people with diabetes.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Arizona NIH-funded |
| Lab location | 1 site (Tucson, United States) |
| Project ID | NIH-11172152 on NIH RePORTER |
What this research studies
This research investigates how diabetes affects the small blood vessels in the heart, leading to problems with blood flow and heart function. It focuses on the mechanisms behind impaired blood vessel relaxation in diabetic patients, particularly how certain molecules like nitric oxide and hydrogen peroxide play a role. By studying these processes in both healthy and diabetic models, the research aims to identify potential treatments that could restore normal blood flow in the heart. Patients may benefit from insights that could lead to new therapies for heart issues related to diabetes.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults with diabetes who are experiencing heart-related issues.
Not a fit: Patients without diabetes or those with obstructive coronary artery disease may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that improve heart function and blood flow in diabetic patients.
How similar studies have performed: Previous research has shown promising results in understanding blood flow issues related to diabetes, making this approach both relevant and potentially impactful.
Where this research is happening
Tucson, United States
- University of Arizona — Tucson, United States (Active)
Researchers
- Principal investigator: Yin, Liya — University of Arizona
- Study coordinator: Yin, Liya
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.