Understanding blood flow issues and exercise challenges in veterans with heart failure.
Mechanisms of Impaired Skeletal Muscle Blood Flow and Exercise Intolerance in Veterans with Heart Failure with Preserved Ejection Fraction: Efficacy of Knee Extensor Training
['FUNDING_OTHER'] · VA SALT LAKE CITY HEALTHCARE SYSTEM · NIH-10854740
This study is looking into why some veterans with heart failure have trouble with blood flow in their muscles, making it hard for them to exercise and enjoy daily activities, and it aims to find ways to help them feel better and move more easily through special knee training.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | VA SALT LAKE CITY HEALTHCARE SYSTEM (nih funded) |
| Locations | 1 site (SALT LAKE CITY, UNITED STATES) |
| Trial ID | NIH-10854740 on ClinicalTrials.gov |
What this research studies
This research investigates the reasons behind poor blood flow in skeletal muscles and the resulting exercise intolerance experienced by veterans suffering from heart failure with preserved ejection fraction (HFpEF). The study aims to explore how these issues affect daily activities and overall quality of life. By focusing on knee extensor training, the research seeks to identify effective rehabilitation strategies that can enhance physical capacity and improve patient outcomes. The approach includes assessing blood flow dynamics and the role of the autonomic nervous system in these patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are veterans diagnosed with heart failure with preserved ejection fraction who experience exercise intolerance.
Not a fit: Patients without heart failure or those with other forms of heart failure not characterized by preserved ejection fraction may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved exercise capacity and quality of life for veterans with heart failure.
How similar studies have performed: Previous research has shown promise in using exercise training to improve outcomes in heart failure patients, suggesting that this approach may be beneficial.
Where this research is happening
SALT LAKE CITY, UNITED STATES
- VA SALT LAKE CITY HEALTHCARE SYSTEM — SALT LAKE CITY, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BUNSAWAT, KANOKWAN — VA SALT LAKE CITY HEALTHCARE SYSTEM
- Study coordinator: BUNSAWAT, KANOKWAN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.