Understanding blood flow between different parts of the pancreas
Blood flow crosstalk between the endocrine and exocrine pancreas
['FUNDING_R01'] · UNIVERSITY OF CHICAGO · NIH-11010778
This study is looking at how blood flows between different parts of the pancreas and how they might work together, which could help us understand conditions like adult-onset diabetes better and lead to new treatment options for patients.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CHICAGO (nih funded) |
| Locations | 1 site (CHICAGO, UNITED STATES) |
| Trial ID | NIH-11010778 on ClinicalTrials.gov |
What this research studies
This research investigates how blood flow between the endocrine and exocrine parts of the pancreas may be bi-directional, contrary to the traditional view that it flows only from the endocrine to the exocrine tissues. By using advanced imaging techniques and in vivo recordings, the study aims to explore the interactions between these two compartments and how they may influence each other's health. The findings could provide insights into the mechanisms behind diseases like adult-onset diabetes and other pancreatic disorders. Patients may benefit from a better understanding of their conditions and potential new treatment approaches based on these interactions.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with adult-onset diabetes or other pancreatic disorders.
Not a fit: Patients with isolated exocrine or endocrine pancreatic conditions without any overlap may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies for pancreatic diseases, particularly adult-onset diabetes.
How similar studies have performed: While the concept of bi-directional blood flow in the pancreas is novel, similar approaches in other organ systems have shown promising results.
Where this research is happening
CHICAGO, UNITED STATES
- UNIVERSITY OF CHICAGO — CHICAGO, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HARA, MANAMI — UNIVERSITY OF CHICAGO
- Study coordinator: HARA, MANAMI
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: adult onset diabetes, Adult-Onset Diabetes Mellitus