Understanding blood flow and pressure in animal models of pulmonary hypertension
Animal Core
This study is all about using advanced tools to better understand how blood flow and pressure change in animals with pulmonary hypertension, which can help researchers learn more about this condition and improve treatments for people who have it.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project ID | NIH-10911057 on NIH RePORTER |
What this research studies
This research focuses on accurately measuring blood flow and pressure changes in animal models that mimic pulmonary hypertension (PH). The Animal Core will provide essential support for researchers by utilizing advanced equipment and techniques to monitor the progression of PH in various animal species, including mice and calves. The team will also assist in breeding specialized transgenic mice and ensure the integrity of biological samples through proper euthanasia and tissue collection. By leveraging state-of-the-art technology, the research aims to enhance our understanding of the cardiovascular changes associated with PH.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with pulmonary hypertension or related cardiovascular conditions who may benefit from advancements in treatment.
Not a fit: Patients without pulmonary hypertension or those not involved in animal model studies may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for pulmonary hypertension by providing insights into the disease mechanisms.
How similar studies have performed: Previous research using similar animal models has shown promise in understanding cardiovascular diseases, indicating that this approach is both relevant and potentially impactful.
Where this research is happening
Aurora, UNITED STATES
- University of Colorado Denver — Aurora, United States (Active)
Researchers
- Principal investigator: Irwin, David Charles — University of Colorado Denver
- Study coordinator: Irwin, David Charles
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.