Understanding blood flow and muscle function after a stroke
Official title: Blood Flow Regulation and Neuromuscular Function Post-Stroke
Funded at Medical College of Wisconsin · NIH-10906947 · Data updated 2026-11-12
This study looks at how blood flow affects muscle strength and tiredness in people who have had a stroke, with the goal of finding ways to help them recover better and enjoy daily activities more easily.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Medical College of Wisconsin NIH-funded |
| Lab location | 1 site (Milwaukee, United States) |
| Project start | August 15, 2023 |
| Project end | July 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $641,044 |
| NIH project number | 5R01HD112258-02 |
| Project ID | NIH-10906947 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who have experienced a stroke and are facing challenges with muscle fatigue and mobility.
✕Less likely to help
Patients who have not had a stroke or those with other unrelated neurological conditions may not benefit from this research.
What this research studies
This research investigates how blood flow regulation affects muscle function in stroke survivors, particularly focusing on neuromuscular fatigability, which is the reduced ability of muscles to perform tasks due to fatigue. The study aims to understand the mechanisms behind impaired blood flow during exercise in individuals who have had a stroke, as this can significantly impact their ability to engage in daily activities. By examining the relationship between blood flow and muscle performance, the research seeks to identify potential rehabilitation strategies that could enhance recovery and improve quality of life for stroke patients.
Why it matters
Potential benefit: If successful, this research could lead to improved rehabilitation techniques that enhance muscle function and endurance in stroke survivors.
How similar studies have gone: Previous research has indicated that addressing blood flow issues can improve muscle function in other populations, suggesting potential for success in this area as well.
Where this research is happening
-
Medical College of Wisconsin
Milwaukee, United States Active
Researchers
- Principal investigator: Durand, Matthew — Medical College of Wisconsin
- Study coordinator: Durand, Matthew
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.