Understanding blood clotting issues in COVID-19 patients

Mechanisms of Thrombosis in SARS CoV-2 Infection

NIH-funded research University of Kentucky · NIH-11050014

This study is looking at how COVID-19 can cause tiny blood clots that might harm your body, and it's for people who have had COVID-19 to help find ways to prevent these issues.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Kentucky NIH-funded
Lab location1 site (Lexington, United States)
Project IDNIH-11050014 on NIH RePORTER

What this research studies

This research investigates how COVID-19 can lead to dangerous blood clotting problems, particularly focusing on small clots known as microclots that can cause tissue damage. The study aims to understand the mechanisms behind these clots, including how certain proteins in the blood are affected during the acute phase of the infection. By examining the interactions between various blood components, the researchers hope to identify potential treatments to prevent these complications. Patients who have experienced COVID-19 may provide valuable insights into these mechanisms.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who have had COVID-19 and are experiencing symptoms related to blood clotting or microclots.

Not a fit: Patients who have not had COVID-19 or those without any symptoms related to blood clotting may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatments for preventing blood clot-related complications in COVID-19 patients.

How similar studies have performed: Other research has indicated that understanding blood clotting mechanisms in viral infections can lead to significant advancements in treatment, suggesting this approach has potential for success.

Where this research is happening

Lexington, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions acute infectionacute phase of SARS-CoV-2 infectionacute SARS-CoV-2 infectionadverse sequelae of coronavirus diseaseadverse sequelae of coronavirus disease 2019
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.