Understanding blood clotting issues after COVID-19 infection and exploring new treatments
Official title: Molecular pathogenesis of COVID-19-associated coagulopathy and new therapeutic approaches
Funded at Scripps Research Institute, the · NIH-11004157 · Data updated 2026-11-12
This study is looking into how COVID-19 can cause blood clotting issues and problems with blood vessels, and it aims to find better treatments to help people who are dealing with these long-term effects.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Scripps Research Institute, the NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project start | January 1, 2024 |
| Project end | December 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $638,826 |
| NIH project number | 5R01HL172048-02 |
| Project ID | NIH-11004157 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals who have experienced severe COVID-19 infections and are facing complications related to blood clotting.
✕Less likely to help
Patients who have not been infected with COVID-19 or those without any blood coagulation issues may not benefit from this research.
What this research studies
This research investigates the blood clotting problems that many patients experience after being infected with COVID-19. It focuses on understanding how the virus affects blood vessels and leads to conditions like blood clots and organ dysfunction. The researchers will explore various potential treatments to reduce these complications and improve patient outcomes. By studying the underlying mechanisms of these issues, the research aims to provide insights that could help manage and treat patients suffering from long-term effects of COVID-19.
Why it matters
Potential benefit: If successful, this research could lead to new therapies that significantly reduce blood clotting complications in COVID-19 patients.
How similar studies have gone: Other research has shown promising results in understanding blood clotting issues related to COVID-19, indicating that this area of study is both relevant and necessary.
Where this research is happening
-
Scripps Research Institute, the
La Jolla, United States Active
Researchers
- Principal investigator: Aiolfi, Roberto — Scripps Research Institute, the
- Study coordinator: Aiolfi, Roberto
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.