Understanding Blood Clotting Disorders Caused by Antibodies
Official title: Protein Production, Structural Biology, and Nucleic Acid Sequencing and Analysis
Funded at Versiti Blood Health, INC. · NIH-11158638 · Data updated 2026-11-12
This project helps scientists better understand certain blood clotting disorders where the body's own antibodies cause problems.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Versiti Blood Health, INC. NIH-funded |
| Lab location | 1 site (Milwaukee, United States) |
| Project start | August 1, 2024 |
| Project end | July 31, 2029 |
| Funding year | 2025 |
| Award (this year) | $412,500 |
| NIH project number | 5P01HL167668-02 |
| Project ID | NIH-11158638 on NIH RePORTER |
Who could benefit from this research
✓Could help
Patients living with antibody-mediated thrombocytopenias, or those at risk for them, are the ultimate focus of the larger research program this core supports.
✕Less likely to help
Patients whose conditions are not related to antibody-mediated thrombocytopenias would not directly benefit from this specific research.
What this research studies
Our body's immune system sometimes mistakenly creates antibodies that attack healthy blood components, leading to conditions like antibody-mediated thrombocytopenias. This project provides specialized services to other researchers who are studying these conditions. We help produce important proteins and antibodies, analyze their structures, and sequence genetic material to understand how these harmful antibodies develop. By centralizing these complex tasks, we aim to speed up discoveries and ensure consistent, high-quality results for the overall research program.
Why it matters
Potential benefit: If successful, this work will deepen our understanding of these complex blood disorders, potentially leading to new ways to diagnose and treat them.
How similar studies have gone: The use of structural biology and advanced sequencing to understand disease mechanisms is a well-established and successful approach in medical research.
Where this research is happening
-
Versiti Blood Health, INC.
Milwaukee, United States Active
Researchers
- Principal investigator: Zhu, Jieqing — Versiti Blood Health, INC.
- Study coordinator: Zhu, Jieqing
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.