Understanding blood clots caused by COVID-19 and exploring new treatments
Determinants of COVID19-induced venous thrombosis and targeted therapy assessed with bioengineered vein-chip
['FUNDING_R01'] · BOSTON UNIVERSITY MEDICAL CAMPUS · NIH-10857160
This study is looking at how COVID-19 might cause blood clots in veins, which can lead to serious problems like strokes, and it's for anyone interested in understanding how the virus affects blood flow and what new treatments might help prevent these issues.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | BOSTON UNIVERSITY MEDICAL CAMPUS (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-10857160 on ClinicalTrials.gov |
What this research studies
This research investigates how COVID-19 can lead to the formation of blood clots in veins, which can result in serious complications like strokes. Using a bioengineered vein-chip model, the study aims to analyze the interactions between the virus, blood components, and the cells lining the blood vessels. By examining these factors, researchers hope to identify the underlying mechanisms of venous thrombosis in COVID-19 patients and develop targeted therapies to prevent these dangerous outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with COVID-19 who are at risk of developing venous thrombosis.
Not a fit: Patients who have not contracted COVID-19 or those without risk factors for venous thrombosis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that reduce the risk of blood clots in COVID-19 patients, improving their overall health outcomes.
How similar studies have performed: Other research has shown promising results in understanding thromboinflammation in COVID-19, making this approach both relevant and potentially impactful.
Where this research is happening
BOSTON, UNITED STATES
- BOSTON UNIVERSITY MEDICAL CAMPUS — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: CONNOR, JOHN H — BOSTON UNIVERSITY MEDICAL CAMPUS
- Study coordinator: CONNOR, JOHN H
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.