Understanding Blood Clots After Injury

Venous Thrombosis After Traumatic Injury

NIH-funded research Mayo Clinic Rochester · NIH-11142547

This project aims to better understand why some trauma patients develop dangerous blood clots, even with preventive care, to help predict and prevent them.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMayo Clinic Rochester NIH-funded
Lab location1 site (Rochester, United States)
Project IDNIH-11142547 on NIH RePORTER

What this research studies

After a serious injury, some patients develop blood clots, known as venous thromboembolism (VTE), which can be very dangerous. Even with standard preventive medicines, many patients still get these clots, often after they leave the hospital. This project will collect detailed information, including blood tests taken right after an injury and patient health history, from many different trauma patients. By looking at how blood clots, platelet activity, and blood vessel health change, alongside factors like BMI and smoking, we hope to find new ways to identify who is most at risk.

Who could benefit from this research

Good fit: This research focuses on patients who have experienced traumatic injuries and are at risk for or have developed venous thromboembolism.

Not a fit: Patients who have not experienced a traumatic injury or are not at risk for blood clots would not directly benefit from this specific research.

Why it matters

Potential benefit: If successful, this work could lead to new ways to predict, diagnose, and treat blood clots in trauma patients, potentially saving lives and reducing complications.

How similar studies have performed: While the problem of VTE after trauma is known, this comprehensive approach to integrate diverse clinical and laboratory data for prediction is novel and largely untested.

Where this research is happening

Rochester, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.