Understanding blood cell development in infants and young adults
Characterizing transient hematopoietic multipotent and megakaryocyte progenitor cells during postnatal development
['FUNDING_FELLOWSHIP'] · LOYOLA UNIVERSITY CHICAGO · NIH-10898648
This study is looking at how blood cells grow and change from the time we're babies to when we become adults, using special mice to help understand these changes better, which could help us learn more about blood disorders that affect kids and young adults.
Quick facts
| Phase | ['FUNDING_FELLOWSHIP'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | LOYOLA UNIVERSITY CHICAGO (nih funded) |
| Locations | 1 site (MAYWOOD, UNITED STATES) |
| Trial ID | NIH-10898648 on ClinicalTrials.gov |
What this research studies
This research investigates how blood cell progenitors develop during the transition from fetal to adult life, focusing on specific types of cells that contribute to blood formation. By studying genetically modified mice, the researchers aim to identify the cellular and molecular changes that occur in hematopoietic stem cells and their progenitors during early development. The approach involves tracking the expression of fluorescent proteins to visualize these cells and their maturation over time. This research could provide insights into blood disorders that affect infants and young adults.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include infants and young adults with blood disorders or those interested in the biological processes of blood cell development.
Not a fit: Patients with established adult-type blood disorders unrelated to developmental processes may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and treatment of blood disorders in infants and young adults.
How similar studies have performed: Previous research has shown promising results in understanding hematopoiesis, but this specific focus on the transition from fetal to adult blood cell development is relatively novel.
Where this research is happening
MAYWOOD, UNITED STATES
- LOYOLA UNIVERSITY CHICAGO — MAYWOOD, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MACK, RYAN — LOYOLA UNIVERSITY CHICAGO
- Study coordinator: MACK, RYAN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.