NIH-funded research R01 grant

Understanding biomedical open-source software to support health research

Official title: SoS: BIO: The Anatomy of Scientific Biomedical Open-Source Software--From Code to Communities

Funded at Carnegie-Mellon University · NIH-11413385 · Data updated 2026-11-12

Aimed at scientists and doctors, this grant studies how biomedical open-source software is built, shared, and kept up-to-date to ensure reliable health research.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionCarnegie-Mellon University
NIH-funded
Lab location1 site (Pittsburgh, United States)
Project startSeptember 5, 2025
Project endJuly 31, 2027
Funding year2026
Award (this year)$246,632
NIH project number5R01GM164731-02
Project IDNIH-11413385 on NIH RePORTER

Who could benefit from this research

Could help

Not applicable (software-focused grant; no direct patient participation)

Less likely to help

No direct patient involvement or benefit in this phase.

What this research studies

This project will map where biomedical open-source software comes from, how it evolves, and how people use it. It will build models to understand maintenance practices, team dynamics, and risks of software being abandoned. It will also connect software health to real research outcomes like productivity and reproducibility using multiple data sources. The work is designed to help researchers rely on trustworthy tools and improve the efficiency of biomedical studies.

Why it matters

Potential benefit: If successful, it could make biomedical software more sustainable, improving study reliability and accelerating health discoveries.

How similar studies have gone: Prior work shows that software maintenance and community practices influence reproducibility and tool reliability in science.

Where this research is happening

  • Carnegie-Mellon University
    Pittsburgh, United States
    Active

Researchers

  • Principal investigator: Vasilescu, Bogdan — Carnegie-Mellon University
  • Study coordinator: Vasilescu, Bogdan

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.