Understanding biological markers of Alzheimer's Disease across the US and India
Official title: Biomarkers of neurodegeneration in the US and India: A cross-national evaluation of the biological underpinnings of ADRD
Funded at Johns Hopkins University · NIH-10939816 · Data updated 2026-11-12
This study is looking at how biological signs of Alzheimer's and related dementias work together with social and economic factors in people from the US and India, to help us understand the disease better and find common patterns that affect its progression.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | September 22, 2024 |
| Project end | August 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $2,365,042 |
| NIH project number | 1RF1AG088003-01 |
| Project ID | NIH-10939816 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals diagnosed with Alzheimer's Disease or related dementias, particularly those from diverse social and economic backgrounds.
✕Less likely to help
Patients who do not have Alzheimer's Disease or related dementias, or those who are not from the US or India, may not benefit from this research.
What this research studies
This research investigates the biological mechanisms underlying Alzheimer's Disease and Related Dementias (ADRD) by comparing data from the US and India. It aims to identify how biological markers of neurodegeneration interact with social and economic factors in different populations. By utilizing harmonized cognitive assessment protocols, the study will explore the relationship between these biological markers and clinical outcomes, providing insights into the disease's progression. This cross-national approach seeks to uncover common pathways that may exist despite varying social contexts.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment strategies for Alzheimer's Disease and related dementias.
How similar studies have gone: Previous research has shown promise in understanding Alzheimer's Disease through cross-national comparisons, indicating potential for success in this novel approach.
Where this research is happening
-
Johns Hopkins University
Baltimore, United States Active
Researchers
- Principal investigator: Gross, Alden L. — Johns Hopkins University
- Study coordinator: Gross, Alden L.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.