Understanding behavior in youth at risk for Huntington disease
Inhibitory Control and Externalizing Behaviors in Youth at Risk for Huntington Disease
This study is looking at the thinking and behavior challenges that young people at risk for Huntington disease might face, like trouble with decision-making, anxiety, and acting impulsively, to help find early signs and improve support for them before any physical symptoms appear.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University Medical Center NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project ID | NIH-10906848 on NIH RePORTER |
What this research studies
This research investigates the cognitive and behavioral challenges faced by youth and young adults who are at risk for Huntington disease (HD). It aims to identify early symptoms and their neurobiological underpinnings, focusing on issues like executive dysfunction, anxiety, and impulsive behaviors. By studying this population, the research seeks to develop methods for measuring these symptoms and understanding their progression before the onset of motor symptoms. The findings could inform future interventions and therapies for those at risk.
Who could benefit from this research
Good fit: Ideal candidates for this research include youth and young adults who are gene carriers or at risk for Huntington disease.
Not a fit: Patients who are not at risk for Huntington disease or do not carry the gene mutation may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier identification and intervention strategies for youth at risk for Huntington disease, potentially improving their quality of life.
How similar studies have performed: Other research has shown success in identifying early cognitive and behavioral changes in at-risk populations, suggesting that this approach is promising.
Where this research is happening
Nashville, United States
- Vanderbilt University Medical Center — Nashville, United States (Active)
Researchers
- Principal investigator: Mcdonell, Katherine — Vanderbilt University Medical Center
- Study coordinator: Mcdonell, Katherine
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.