NIH-funded research R21 grant

Understanding barriers to opioid tapering and transition for older patients

Official title: Providers and Older Pain Patients with Prescription Opioid Dependence: A Qualitative Study to Understand Barriers to Opioid Taper, Cessation, and Transition to Buprenorphine.

Funded at Saint Louis University · NIH-10671358 · Data updated 2026-11-12

This study is looking at the difficulties older adults and their doctors face when trying to reduce or stop using prescription opioids and switch to a different medication called buprenorphine, so they can better understand how to improve conversations and decisions about pain management for seniors.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionSaint Louis University
NIH-funded
Lab location1 site (Saint Louis, United States)
Project startSeptember 19, 2023
Project endSeptember 18, 2025
Funding year2023
Award (this year)$416,625
NIH project number1R21AG076812-01A1
Project IDNIH-10671358 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are older adults aged 50 and above who are currently using prescription opioids and may be experiencing dependence.

Less likely to help

Patients who are not using prescription opioids or are younger than 50 years old may not benefit from this research.

What this research studies

This research investigates the challenges faced by older patients and their healthcare providers regarding the tapering and cessation of prescription opioids, as well as the transition to buprenorphine. By using qualitative methods, the study aims to gather insights into the beliefs and experiences of both patients and providers, particularly focusing on the unique health risks associated with chronic opioid use in older adults. The goal is to identify barriers that prevent effective communication and decision-making about opioid management in this population, ultimately leading to improved care strategies.

Why it matters

Potential benefit: If successful, this research could lead to better management of opioid dependence in older patients, reducing health risks and improving overall quality of life.

How similar studies have gone: While there is limited research specifically targeting older patients in this area, similar qualitative approaches have shown promise in understanding patient-provider dynamics in other populations.

Where this research is happening

  • Saint Louis University
    Saint Louis, United States
    Active

Researchers

  • Principal investigator: Grucza, Richard a — Saint Louis University
  • Study coordinator: Grucza, Richard a

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.