Understanding balance issues in patients with specific types of benign tumors.
Official title: Vestibular dysfunction in patients with sporadic vestibular schwannomas and NF2-related schwannomatosis.
Funded at Massachusetts Eye and Ear Infirmary · NIH-11047133 · Data updated 2026-11-12
This study looks at how benign tumors on the vestibular nerve, called vestibular schwannomas, affect balance and dizziness in patients, including those with a genetic condition called neurofibromatosis type 2, to better understand how treatment impacts their symptoms.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts Eye and Ear Infirmary NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | May 1, 2025 |
| Project end | April 30, 2030 |
| Funding year | 2025 |
| Award (this year) | $620,240 |
| NIH project number | 1R01DC021434-01A1 |
| Project ID | NIH-11047133 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals diagnosed with sporadic vestibular schwannomas or those with neurofibromatosis type 2-related schwannomatosis experiencing vestibular dysfunction.
✕Less likely to help
Patients without vestibular schwannomas or those with other unrelated balance disorders may not benefit from this research.
What this research studies
This research investigates how vestibular schwannomas, which are benign tumors affecting the vestibular nerve, impact balance and vestibular function in patients. It focuses on both sporadic cases and those related to neurofibromatosis type 2, aiming to understand the underlying mechanisms of vestibular dysfunction. By analyzing vestibular metrics before and after standard treatments like surgery or radiation, the study seeks to correlate these metrics with patient outcomes. The research employs a detailed observational approach to assess the relationship between vestibular function and various clinical parameters.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and management of balance disorders in patients with vestibular schwannomas.
How similar studies have gone: Previous research has shown promising results in understanding vestibular dysfunction in similar patient populations, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Massachusetts Eye and Ear Infirmary
Boston, United States Active
Researchers
- Principal investigator: Lewis, Richard F — Massachusetts Eye and Ear Infirmary
- Study coordinator: Lewis, Richard F
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.