NIH-funded research NIH-funded research

Understanding B cell responses in food allergies

Official title: Innovations in Functional B Cell Epitope Discovery for Food Allergy

Funded at Stanford University · NIH-11205412 · Data updated 2026-11-12

This study is looking at how your immune system's B cells react to different food allergens to understand what makes people allergic, with the hope of finding better treatments for food allergies, especially through a method called oral immunotherapy, and it involves analyzing blood samples from patients like you.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionStanford University
NIH-funded
Lab location1 site (Stanford, United States)
Project startSeptember 30, 2024
Project endSeptember 29, 2025
Funding year2024
Award (this year)$1,313,458
NIH project number75N93024C00075-0-9999-1
Project IDNIH-11205412 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals diagnosed with food allergies who are willing to participate in blood sample analysis.

Less likely to help

Patients without food allergies or those who do not have a specific allergic response to food may not benefit from this research.

What this research studies

This research investigates how human B cells respond to different food allergens, focusing on the specific parts of these allergens that trigger allergic reactions. By analyzing the B cell receptors and antibodies from patients with food allergies, the study aims to uncover the variations in immune responses among individuals. The approach includes examining the epitope targets that these B cells recognize, which could lead to better treatments for food allergies, particularly through oral immunotherapy. Patients may have their blood samples analyzed to identify their unique B cell responses.

Why it matters

Potential benefit: If successful, this research could lead to more personalized and effective treatments for individuals with food allergies.

How similar studies have gone: Previous research has shown promise in understanding B cell responses in allergies, suggesting that this approach could yield valuable insights.

Where this research is happening

  • Stanford University
    Stanford, United States
    Active

Researchers

  • Principal investigator: Boyd, Scott — Stanford University
  • Study coordinator: Boyd, Scott

Related research

Other NIH-funded projects on the same topics.

  • New Horizons in preventing and treating food allergy

    A Johns Hopkins-led effort aims to advance how we prevent and treat food allergies across all ages by coordinating high-quality studies and developing better therapies.

    NIH research Johns Hopkins University · Baltimore, United States · NIH-11600582

  • New Horizons in Food Allergy Prevention and Treatment

    A large, multi-site program at Johns Hopkins aims to advance prevention and treatment of food allergies across all ages.

    NIH research Johns Hopkins University · Baltimore, United States · NIH-11580809

  • Food allergy outcomes by race/ethnicity from infancy through adolescence

    This study follows children with food allergies over time to understand how race and ethnicity relate to allergy management, outcomes, and quality of life.

    NIH research Northwestern University · Chicago, United States · NIH-11579222

  • Gut-brain links in food allergy responses

    A research grant is exploring how signals between the gut and brain drive dangerous reactions to foods, with the goal of helping people with food allergies.

    NIH research Yale University · New Haven, United States · NIH-11551492

  • Targeting gut microbes to restore food-tolerance in adults

    Aims to understand how gut bacteria and the lining of the gut interact to keep people with food allergies tolerant to what they eat.

    NIH research Boston Children's Hospital · Boston, United States · NIH-11551491

  • Environment and early-life exposures shaping food allergy in children

    This grant looks at how a child’s first year and their home environment may influence whether they develop food allergies, focusing on indoor exposures and microbes.

    NIH research Univ of North Carolina Chapel Hill · Chapel Hill, United States · NIH-11450430

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.