Understanding autoimmune diseases and their biomarkers
Collaborative Project
['FUNDING_OTHER'] · WEILL MEDICAL COLL OF CORNELL UNIV · NIH-11080356
This study is looking for ways to better understand and predict how systemic lupus erythematosus (SLE) affects people, especially women, by finding helpful markers in the blood that can show how the disease is progressing and how well treatments are working, and we invite patients to share their samples or information to support this important research.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | WEILL MEDICAL COLL OF CORNELL UNIV (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-11080356 on ClinicalTrials.gov |
What this research studies
This research investigates systemic autoimmune diseases, particularly systemic lupus erythematosus (SLE), which affects a significant number of individuals, especially women. The project aims to identify robust biomarkers that can predict the progression of SLE, organ involvement, and responses to treatment. By exploring the role of anti-nuclear antibodies and activated T cell-derived exosomes, the research seeks to uncover the mechanisms behind immune activation and how these insights can be used for therapeutic purposes. Patients may be involved in providing samples or data to help advance this understanding.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with systemic lupus erythematosus or other systemic autoimmune diseases.
Not a fit: Patients with autoimmune conditions not related to systemic lupus erythematosus may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic tools and treatments for patients with systemic lupus erythematosus and other autoimmune diseases.
How similar studies have performed: Previous research has shown promise in identifying biomarkers for autoimmune diseases, making this approach both relevant and potentially impactful.
Where this research is happening
NEW YORK, UNITED STATES
- WEILL MEDICAL COLL OF CORNELL UNIV — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LYDEN, DAVID CHARLES — WEILL MEDICAL COLL OF CORNELL UNIV
- Study coordinator: LYDEN, DAVID CHARLES
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.