Understanding autism symptoms in children with Down syndrome

Evaluating ASD Symptomatology in Children with Down Syndrome

['FUNDING_R21'] · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · NIH-10294431

This study is looking at how autism symptoms show up in children with Down syndrome, and it's working to create better ways to measure these symptoms so that kids can get the best care and support possible.

Quick facts

Phase['FUNDING_R21']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN (nih funded)
Locations1 site (CHAMPAIGN, UNITED STATES)
Trial IDNIH-10294431 on ClinicalTrials.gov

What this research studies

This research investigates the prevalence and characteristics of autism spectrum disorder (ASD) symptoms in children with Down syndrome (DS). It aims to develop reliable tools for measuring these symptoms, which are crucial for improving treatment and care. By evaluating the psychometric properties of existing ASD measures and conducting in-depth assessments of symptom profiles, the study seeks to enhance the understanding of how ASD manifests in children with DS. This will ultimately support better clinical trial designs and treatment monitoring.

Who could benefit from this research

Good fit: Ideal candidates for this research are children diagnosed with Down syndrome, particularly those who may also exhibit symptoms of autism spectrum disorder.

Not a fit: Patients without Down syndrome or those who do not exhibit any symptoms of autism spectrum disorder may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved diagnostic tools and treatment strategies for children with Down syndrome who also have autism spectrum disorder.

How similar studies have performed: Other research has shown success in developing diagnostic tools for autism in different populations, but this specific focus on children with Down syndrome is relatively novel.

Where this research is happening

CHAMPAIGN, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.