Understanding asthma risks in children born extremely preterm
Official title: Asthma among children born extremely preterm: multi-omic perinatal predictors
Funded at Univ of North Carolina Chapel Hill · NIH-10992654 · Data updated 2026-11-12
This study is looking at how things like genes and the environment during pregnancy and early life can affect the chances of children born very early developing asthma, so we can find better ways to prevent it.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Univ of North Carolina Chapel Hill NIH-funded |
| Lab location | 1 site (Chapel Hill, United States) |
| Project start | December 1, 2023 |
| Project end | November 30, 2025 |
| Funding year | 2025 |
| Award (this year) | $116,625 |
| NIH project number | 5R21HL172136-02 |
| Project ID | NIH-10992654 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are children who were born extremely preterm and are currently experiencing respiratory issues.
✕Less likely to help
Patients who were not born preterm or do not have a history of respiratory issues may not benefit from this research.
What this research studies
This research investigates the factors that contribute to asthma in children who were born extremely preterm. It focuses on how genetic and environmental influences during pregnancy and early life can affect the development of asthma. By studying the placenta and its role in fetal development, the research aims to identify early predictors of asthma and improve prevention strategies. The approach includes analyzing biological samples and data from a specific cohort of preterm infants.
Why it matters
Potential benefit: If successful, this research could lead to better prevention and treatment strategies for asthma in children born preterm.
How similar studies have gone: Previous research has shown promising results in understanding chronic conditions in preterm infants, suggesting that this approach could yield valuable insights.
Where this research is happening
-
Univ of North Carolina Chapel Hill
Chapel Hill, United States Active
Researchers
- Principal investigator: Gower, William a — Univ of North Carolina Chapel Hill
- Study coordinator: Gower, William a
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.