Understanding asthma risk factors and types in minority children
Official title: Epigenomics of asthma risk factors and clinical subtypes in minority children
Funded at University of California, San Francisco · NIH-10753536 · Data updated 2026-11-12
This study is looking at how genes and the environment affect asthma in minority children, hoping to find out what makes asthma different for kids from various backgrounds so that we can create better treatments just for them.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project start | January 1, 2021 |
| Project end | November 30, 2025 |
| Funding year | 2024 |
| Award (this year) | $700,325 |
| NIH project number | 5R01HL155024-04 |
| Project ID | NIH-10753536 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are minority children aged 0-11 years who have been diagnosed with asthma or are at risk of developing asthma.
✕Less likely to help
Patients who do not belong to minority groups or those over the age of 11 may not receive direct benefits from this research.
What this research studies
This research investigates how different genetic and environmental factors contribute to asthma in minority children. It aims to identify specific cell types, genes, and pathways that are altered due to exposure to various clinical risk factors. By analyzing the epigenetic profiles of children with and without asthma, the study seeks to uncover the biological mechanisms behind asthma's varying prevalence and severity among different racial and ethnic groups. This could lead to better-targeted treatments and interventions for affected children.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and management of asthma in minority children, potentially reducing health disparities.
How similar studies have gone: Previous research has shown success in identifying genetic and environmental factors influencing asthma, but this study aims to explore novel epigenetic approaches, making it a potentially groundbreaking effort.
Where this research is happening
-
University of California, San Francisco
San Francisco, United States Active
Researchers
- Principal investigator: Ziv, Elad — University of California, San Francisco
- Study coordinator: Ziv, Elad
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.