Understanding asthma in children who frequently experience attacks
Multi-omics of the Frequent Exacerbator Asthmatic
This study is looking at children with asthma who have frequent attacks to understand what causes these flare-ups, especially in families living in urban areas with limited resources, so we can find better ways to help them manage their condition.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cincinnati Childrens Hosp Med Ctr NIH-funded |
| Lab location | 1 site (Cincinnati, United States) |
| Project ID | NIH-11035168 on NIH RePORTER |
What this research studies
This research investigates the characteristics of children with asthma who experience frequent exacerbations, defined as having two or more attacks per year. It focuses on understanding the underlying biological and environmental factors contributing to these exacerbations, particularly in low-income urban populations. By analyzing multi-omics data, which includes genetic, environmental, and clinical information, the study aims to identify patterns that could lead to better management strategies for these patients. The research is conducted at Cincinnati Children's Hospital Medical Center, where a team of experts will work closely with affected families to gather data and insights.
Who could benefit from this research
Good fit: Ideal candidates for this research are children aged 0-11 years who have a history of frequent asthma exacerbations.
Not a fit: Patients with well-controlled asthma who do not experience frequent exacerbations may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies and reduced asthma attacks in children, enhancing their quality of life.
How similar studies have performed: Previous research has shown that understanding the biological underpinnings of asthma can lead to significant advancements in treatment, making this approach promising.
Where this research is happening
Cincinnati, United States
- Cincinnati Childrens Hosp Med Ctr — Cincinnati, United States (Active)
Researchers
- Principal investigator: Khurana Hershey, Gurjit K. — Cincinnati Childrens Hosp Med Ctr
- Study coordinator: Khurana Hershey, Gurjit K.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.