Understanding aspiration risks in survivors of acute respiratory failure

Aspiration in Acute Respiratory Failure Survivors

NIH-funded research University of Colorado Denver · NIH-11080989

This study is looking at how to spot patients who might have trouble swallowing safely after they’ve been on a breathing machine, so we can help prevent serious problems like pneumonia and make their recovery easier.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Colorado Denver NIH-funded
Lab location1 site (Aurora, UNITED STATES)
Project IDNIH-11080989 on NIH RePORTER

What this research studies

This research investigates the risks of aspiration in patients who have survived acute respiratory failure and required mechanical ventilation. It aims to develop a decision-making algorithm to identify patients at high risk for aspiration after extubation, which can lead to serious complications like pneumonia and increased hospital mortality. The study will involve a multi-center approach, utilizing established research teams from institutions like Colorado, Boston University, Stanford, and Yale to gather comprehensive data on this issue. By understanding the factors that contribute to aspiration, the research seeks to improve patient outcomes and reduce caregiver burden.

Who could benefit from this research

Good fit: Ideal candidates for this research are patients who have recently survived an episode of acute respiratory failure and required mechanical ventilation.

Not a fit: Patients who have not experienced acute respiratory failure or those who are not at risk for aspiration may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better identification and management of patients at risk for aspiration, ultimately improving their recovery and quality of life.

How similar studies have performed: Previous research has shown promising results in identifying risk factors for aspiration in similar patient populations, indicating that this approach has potential for success.

Where this research is happening

Aurora, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.