Understanding aspiration risks in survivors of acute respiratory failure
Official title: Aspiration in Acute Respiratory Failure Survivors
Funded at University of Colorado Denver · NIH-11080989 · Data updated 2026-11-12
This study is looking at how to spot patients who might have trouble swallowing safely after they’ve been on a breathing machine, so we can help prevent serious problems like pneumonia and make their recovery easier.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project start | August 23, 2021 |
| Project end | May 31, 2026 |
| Funding year | 2025 |
| Award (this year) | $634,798 |
| NIH project number | 5R01NR019989-05 |
| Project ID | NIH-11080989 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients who have recently survived an episode of acute respiratory failure and required mechanical ventilation.
✕Less likely to help
Patients who have not experienced acute respiratory failure or those who are not at risk for aspiration may not benefit from this research.
What this research studies
This research investigates the risks of aspiration in patients who have survived acute respiratory failure and required mechanical ventilation. It aims to develop a decision-making algorithm to identify patients at high risk for aspiration after extubation, which can lead to serious complications like pneumonia and increased hospital mortality. The study will involve a multi-center approach, utilizing established research teams from institutions like Colorado, Boston University, Stanford, and Yale to gather comprehensive data on this issue. By understanding the factors that contribute to aspiration, the research seeks to improve patient outcomes and reduce caregiver burden.
Why it matters
Potential benefit: If successful, this research could lead to better identification and management of patients at risk for aspiration, ultimately improving their recovery and quality of life.
How similar studies have gone: Previous research has shown promising results in identifying risk factors for aspiration in similar patient populations, indicating that this approach has potential for success.
Where this research is happening
-
University of Colorado Denver
Aurora, United States Active
Researchers
- Principal investigator: Moss, Marc — University of Colorado Denver
- Study coordinator: Moss, Marc
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.