Understanding Arginine and Beta Cell Function in Children with Type 2 Diabetes
Investigation of Arginine Metabolism and Its Effects on Beta Cell Function in Children with Type 2 Diabetes
This project explores how a nutrient called arginine affects the cells in the pancreas that make insulin in children who have type 2 diabetes.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-11142550 on NIH RePORTER |
What this research studies
Type 2 diabetes in children is a growing concern, often leading to a rapid decline in the body's ability to produce insulin. We want to understand if the way the body uses arginine, an amino acid, plays a role in this condition. Our goal is to see if giving extra arginine could help improve how the insulin-producing cells in the pancreas work for children with type 2 diabetes. We will use special techniques to measure arginine levels and its effects within these cells.
Who could benefit from this research
Good fit: Ideal candidates for future related studies would be children diagnosed with type 2 diabetes.
Not a fit: Patients without type 2 diabetes or those outside the pediatric age range may not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to new ways to help children with type 2 diabetes maintain their insulin production and manage their condition more effectively.
How similar studies have performed: Arginine is known to stimulate insulin secretion, and this work builds on existing knowledge to specifically address its role in pediatric type 2 diabetes.
Where this research is happening
Houston, United States
- Baylor College of Medicine — Houston, United States (Active)
Researchers
- Principal investigator: Tosur, Mustafa — Baylor College of Medicine
- Study coordinator: Tosur, Mustafa
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.