NIH-funded research Career grant

Understanding anxiety related to eating in people with anorexia nervosa

Official title: Longitudinal Assessment of Eating-related Anxiety in Anorexia Nervosa

Funded at Johns Hopkins University · NIH-11289574 · Data updated 2026-11-12

This study is looking at how anxiety about eating affects people with anorexia nervosa and aims to understand how facing their fears around certain foods can help them over time, while also using brain scans to see who might benefit most from treatment.

More Anxiety research and trials

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionJohns Hopkins University
NIH-funded
Lab location1 site (Baltimore, United States)
Project startMarch 1, 2022
Project endFebruary 28, 2027
Funding year2025
Award (this year)$54,000
NIH project number3K01MH127178-04S1
Project IDNIH-11289574 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals diagnosed with anorexia nervosa who experience significant anxiety related to eating.

Less likely to help

Patients who do not have anorexia nervosa or those who do not experience eating-related anxiety may not benefit from this research.

What this research studies

This research investigates the anxiety that individuals with anorexia nervosa experience around eating, particularly focusing on how this anxiety can lead to avoidance of certain foods. The study will use behavioral experiments and advanced imaging techniques to explore how these anxiety responses can change over time with exposure to feared foods. Additionally, machine learning will be employed to predict which patients are more likely to respond to treatment based on their brain activity. The goal is to uncover the underlying mechanisms of eating-related anxiety and improve treatment strategies for anorexia nervosa.

Why it matters

Potential benefit: If successful, this research could lead to more effective treatments for anorexia nervosa by addressing the anxiety that contributes to the disorder.

How similar studies have gone: Previous research has shown promise in using exposure-based therapies to reduce anxiety in eating disorders, suggesting that this approach may be effective.

Where this research is happening

  • Johns Hopkins University
    Baltimore, United States
    Active

Researchers

  • Principal investigator: Smith, Kimberly — Johns Hopkins University
  • Study coordinator: Smith, Kimberly

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.