Understanding anxiety in young girls and its connection to sleep
Official title: A translational approach for identifying factors and mechanisms underlying pathological anxiety in preadolescent girls
Funded at University of Wisconsin-Madison · NIH-11080942 · Data updated 2026-11-12
This study is looking at how anxiety affects sleep in young girls, and it aims to find out what’s happening in the brain by comparing girls to monkeys, so we can better understand and help kids who struggle with anxiety.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Wisconsin-Madison NIH-funded |
| Lab location | 1 site (Madison, United States) |
| Project start | June 21, 2023 |
| Project end | April 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $660,744 |
| NIH project number | 5R01MH132671-03 |
| Project ID | NIH-11080942 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are preadolescent girls experiencing symptoms of anxiety or related sleep disturbances.
✕Less likely to help
Patients who do not experience anxiety symptoms or are outside the preadolescent age range may not benefit from this research.
What this research studies
This research investigates the factors and mechanisms that contribute to pathological anxiety in preadolescent girls, particularly focusing on how anxiety symptoms are related to sleep disturbances. By using a translational approach, the study will compare neuroimaging and EEG sleep data from both preadolescent girls and female rhesus monkeys to uncover insights into the neural circuits involved in anxiety. The goal is to better understand the relationship between anxiety and sleep, which is crucial for emotional regulation and learning in children. This research aims to identify early indicators of anxiety disorders to inform prevention and treatment strategies.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment of anxiety disorders in young girls, potentially reducing the risk of developing more severe mental health issues later in life.
How similar studies have gone: Previous research has shown promising results in understanding anxiety through similar neuroimaging and behavioral approaches, indicating that this study builds on established methodologies.
Where this research is happening
-
University of Wisconsin-Madison
Madison, United States Active
Researchers
- Principal investigator: Kalin, Ned H — University of Wisconsin-Madison
- Study coordinator: Kalin, Ned H
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.