Understanding anxiety in adolescents with autism through body responses

Assessing Anxiety in Adolescents with Autism Spectrum Disorder: The Role of Autonomic Activity as a Biomarker

['FUNDING_CAREER'] · UNIV OF MARYLAND, COLLEGE PARK · NIH-11051908

This study is looking at how the body's natural responses can help us understand anxiety in teenagers with autism, and it aims to find patterns that show how anxiety levels change in different situations and among different backgrounds.

Quick facts

Phase['FUNDING_CAREER']
Study typeNih_funding
SexAll
SponsorUNIV OF MARYLAND, COLLEGE PARK (nih funded)
Locations1 site (COLLEGE PARK, UNITED STATES)
Trial IDNIH-11051908 on ClinicalTrials.gov

What this research studies

This research investigates how autonomic activity, which reflects the body's physiological responses, can serve as a biomarker for anxiety in adolescents with autism spectrum disorder (ASD). By collecting data from both autistic and non-autistic adolescents, the study aims to identify patterns of autonomic activity that correlate with anxiety levels. The research will also consider the impact of ecological context and race on these relationships, utilizing real-time monitoring techniques to gather data in natural settings. This approach seeks to provide a more objective measure of anxiety in this population, which has historically faced challenges in accurate diagnosis.

Who could benefit from this research

Good fit: Ideal candidates for this research are adolescents aged 0-14 years who are diagnosed with autism spectrum disorder, particularly those experiencing anxiety symptoms.

Not a fit: Patients who do not have autism spectrum disorder or who are outside the age range of 0-14 years may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved methods for identifying and managing anxiety in adolescents with autism, ultimately enhancing their mental health and quality of life.

How similar studies have performed: Previous research has shown promise in using physiological measures to assess anxiety in various populations, suggesting that this approach may yield valuable insights for adolescents with autism.

Where this research is happening

COLLEGE PARK, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: adolescent with autism spectrum disorder

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.