Understanding antibiotic resistance in throat infections caused by gonorrhea
Characterizing Antimicrobial Resistance in Pharyngeal Neisseria gonorrhoeae Infections and the Role of Commensal Neisseria Species
This study is looking into how some throat infections caused by gonorrhea bacteria can become resistant to antibiotics, even when they don’t show any symptoms, and it’s for anyone interested in understanding how these infections spread and what role other bacteria might play in this process.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10869982 on NIH RePORTER |
What this research studies
This research investigates the emergence of antibiotic-resistant Neisseria gonorrhoeae infections in the throat, which often show no symptoms. It aims to understand how these infections contribute to the spread of resistance and how commensal Neisseria species may act as reservoirs for this resistance. The study will involve collecting and analyzing clinical, microbiological, genomic, and behavioral data to fill knowledge gaps in the epidemiology of these infections. The research will also provide training for the investigator in various scientific methodologies.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have been diagnosed with pharyngeal Neisseria gonorrhoeae infections or are at risk of such infections.
Not a fit: Patients with non-gonococcal throat infections or those who do not have access to the research site may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostics and treatment strategies for gonorrhea infections, ultimately reducing the spread of antibiotic resistance.
How similar studies have performed: Previous research has shown success in understanding antibiotic resistance patterns in other bacterial infections, suggesting that this approach could yield valuable insights.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Melendez, Johan Humberto — Johns Hopkins University
- Study coordinator: Melendez, Johan Humberto
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.