Understanding antibiotic resistance in bacteria
Clinical Isolate Core (Core B)
This study is looking at how some bacteria, especially Acinetobacter baumannii, can survive antibiotic treatments, and by collecting samples from hospitals, it hopes to find better ways to treat infections, which could help patients get more effective care.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-11037945 on NIH RePORTER |
What this research studies
This research focuses on collecting and analyzing clinical bacterial isolates to evaluate antibiotic heteroresistance, which is the ability of bacteria to survive antibiotic treatment. A multidisciplinary team will gather samples from various sources, including hospitals and health programs, to study how certain bacteria, particularly Acinetobacter baumannii, respond to antibiotics. By profiling these isolates, the research aims to enhance our understanding of antibiotic resistance patterns and improve treatment strategies for infections. Patients may benefit from improved antibiotic therapies as a result of this research.
Who could benefit from this research
Good fit: Ideal candidates for this research include patients with infections caused by Acinetobacter baumannii or other multi-drug resistant organisms.
Not a fit: Patients with infections caused by bacteria that are not part of the Acinetobacter baumannii complex may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for infections caused by antibiotic-resistant bacteria.
How similar studies have performed: Previous research has shown success in understanding antibiotic resistance through similar methodologies, indicating a promising approach.
Where this research is happening
Atlanta, United States
- Emory University — Atlanta, United States (Active)
Researchers
- Principal investigator: Jacob, Jesse Thomas — Emory University
- Study coordinator: Jacob, Jesse Thomas
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.