Understanding anesthesia's role in perioperative organ injury with wireless soft implants
Official title: Understanding the role of anesthesia in perioperative organ injury via wireless soft implants
Funded at Dartmouth College · NIH-11394875 · Data updated 2026-11-12
A research project from Dartmouth College is exploring how anesthesia contributes to organ injury after surgery using new wireless soft implants.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Dartmouth College NIH-funded |
| Lab location | 1 site (Hanover, United States) |
| Project start | September 1, 2025 |
| Project end | June 30, 2030 |
| Funding year | 2026 |
| Award (this year) | $441,626 |
| NIH project number | 5R35GM159840-02 |
| Project ID | NIH-11394875 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are surgical patients at risk for perioperative organ injury who would benefit from improved monitoring approaches and future translation of protective strategies.
✕Less likely to help
Patients not undergoing surgery or without risk of perioperative organ injury may not directly benefit.
What this research studies
This project aims to uncover how anesthesia affects organ health during and after surgery, with a focus on kidneys and other organs. Researchers will develop and test wireless, soft implants to monitor pathogenic processes in real time. The goal is to reveal mechanisms behind perioperative organ injury and identify potential protective anesthesia strategies that could improve recovery for surgical patients.
Why it matters
Potential benefit: If successful, it could lead to safer anesthesia practices and better prevention of organ injury after surgery.
How similar studies have gone: Prior work has shown the promise of advanced monitoring and anesthesia-related protection in ischemia-reperfusion scenarios, but this approach is innovative in using wireless soft implants to study POI.
Where this research is happening
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Dartmouth College
Hanover, United States Active
Researchers
- Principal investigator: Ouyang, Wei — Dartmouth College
- Study coordinator: Ouyang, Wei
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.