Understanding and treating pyoderma gangrenosum
Official title: Diagnostic and treatment landscape of pyoderma gangrenosum
Funded at Oregon Health & Science University · NIH-10898068 · Data updated 2026-11-12
This study is looking into better ways to diagnose and treat pyoderma gangrenosum, a painful skin condition that causes ulcers, so that patients can have more effective options and improved quality of life.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Oregon Health & Science University NIH-funded |
| Lab location | 1 site (Portland, United States) |
| Project start | August 2, 2023 |
| Project end | July 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $207,075 |
| NIH project number | 5R01AR083110-02 |
| Project ID | NIH-10898068 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults aged 21 and older who have been diagnosed with pyoderma gangrenosum.
✕Less likely to help
Patients with other skin conditions that do not involve pyoderma gangrenosum may not benefit from this research.
What this research studies
This research focuses on pyoderma gangrenosum (PG), a rare and painful skin condition that leads to chronic ulcers and significant quality of life issues. The study aims to improve diagnostic criteria and treatment options for PG, which are currently limited and often based on expert opinion rather than solid clinical evidence. Researchers will explore the effectiveness of existing treatments and investigate new therapeutic alternatives, including biologics, to enhance patient outcomes. By addressing the challenges of misdiagnosis and treatment variability, this research seeks to provide clearer pathways for managing PG.
Why it matters
Potential benefit: If successful, this research could lead to more accurate diagnoses and effective treatments for patients suffering from pyoderma gangrenosum.
How similar studies have gone: While there has been limited research on pyoderma gangrenosum, similar approaches in studying rare inflammatory conditions have shown promise in improving treatment outcomes.
Where this research is happening
-
Oregon Health & Science University
Portland, United States Active
Researchers
- Principal investigator: Ortega Loayza, Alex — Oregon Health & Science University
- Study coordinator: Ortega Loayza, Alex
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.