Understanding and Treating Liver Disease (MASLD/NAFLD)

Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN)

['FUNDING_U01'] · UNIVERSITY OF SOUTHERN CALIFORNIA · NIH-11168837

This network brings together experts to better understand and find new treatments for a common liver condition called MASLD, also known as fatty liver disease.

Quick facts

Phase['FUNDING_U01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF SOUTHERN CALIFORNIA (nih funded)
Locations1 site (Los Angeles, UNITED STATES)
Trial IDNIH-11168837 on ClinicalTrials.gov

What this research studies

Metabolic dysfunction associated steatotic liver disease (MASLD), previously known as nonalcoholic fatty liver disease (NAFLD), affects many people and can lead to serious liver problems like cirrhosis and liver cancer. This long-standing network collects information from adults and children with MASLD/NAFLD to understand how the disease progresses over time. They also conduct clinical trials to test new treatments and gather samples like blood and liver tissue. This comprehensive approach helps researchers learn more about the disease and develop better ways to help patients.

Who could benefit from this research

Good fit: Ideal candidates for participation in this network's activities include adults and children with metabolic dysfunction associated steatotic liver disease (MASLD), previously known as nonalcoholic fatty liver disease (NAFLD).

Not a fit: Patients without MASLD/NAFLD would not directly benefit from participating in this specific research network.

Why it matters

Potential benefit: If successful, this work could lead to a deeper understanding of MASLD/NAFLD and new, more effective treatments for patients.

How similar studies have performed: This network has been established since 2002, indicating a sustained effort with ongoing observational studies and clinical trials, building upon previous findings.

Where this research is happening

Los Angeles, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Cancers

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.