Understanding and treating liver cirrhosis
San Diego Cirrhosis Clinical Research Network
This study is looking to understand liver cirrhosis better and find out if a common cholesterol medication called atorvastatin can help prevent serious problems like liver cancer in people with this condition, so we can improve care for patients.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project ID | NIH-10909252 on NIH RePORTER |
What this research studies
This research focuses on establishing a network to study liver cirrhosis, which has become increasingly prevalent and is a leading cause of death in the U.S. The project aims to conduct a large, multicenter study to identify factors that predict mortality in cirrhosis patients and to evaluate the effectiveness of statins, particularly atorvastatin, in preventing complications like liver cancer. By gathering data from a diverse group of patients, the research seeks to develop better treatment strategies for those suffering from cirrhosis.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with liver cirrhosis, particularly those from diverse ethnic backgrounds.
Not a fit: Patients without a diagnosis of liver cirrhosis or those with other unrelated liver conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment options and better management of liver cirrhosis, potentially reducing mortality rates.
How similar studies have performed: Previous studies have shown promising results regarding the use of statins in cirrhosis patients, but this research aims to confirm these findings through larger, randomized trials.
Where this research is happening
La Jolla, United States
- University of California, San Diego — La Jolla, United States (Active)
Researchers
- Principal investigator: Loomba, Rohit — University of California, San Diego
- Study coordinator: Loomba, Rohit
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.