Understanding and treating learning challenges in children affected by prenatal alcohol exposure
Mechanisms and treatments of learning deficits in Fetal Alcohol Spectrum Disorders
This study is looking at how drinking alcohol during pregnancy affects kids' thinking and behavior, and it aims to find ways to help children with Fetal Alcohol Spectrum Disorders (FASD) learn better by exploring specific biological factors and possible treatments.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Children's Research Institute NIH-funded |
| Lab location | 1 site (Washington, United States) |
| Project ID | NIH-11193149 on NIH RePORTER |
What this research studies
This research investigates the long-term effects of prenatal alcohol exposure on children's cognitive and behavioral development. It focuses on identifying specific biological mechanisms, particularly the role of the potassium channel KCNN2 and Apolipoprotein E (APOE), that contribute to learning deficits in children with Fetal Alcohol Spectrum Disorders (FASD). The study aims to explore potential treatments, including pharmacological interventions that could improve learning outcomes. By examining both animal models and human subjects, the research seeks to validate therapeutic targets that could lead to effective interventions for affected children.
Who could benefit from this research
Good fit: Ideal candidates for this research are children aged 0-11 years who have been diagnosed with Fetal Alcohol Spectrum Disorders or have a history of prenatal alcohol exposure.
Not a fit: Patients who do not have a history of prenatal alcohol exposure or those outside the age range of 0-11 years may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments that significantly improve learning and cognitive function in children affected by prenatal alcohol exposure.
How similar studies have performed: Previous research has shown promising results in addressing similar cognitive deficits associated with prenatal alcohol exposure, indicating that this approach has potential for success.
Where this research is happening
Washington, United States
- Children's Research Institute — Washington, United States (Active)
Researchers
- Principal investigator: Torii, Masaaki — Children's Research Institute
- Study coordinator: Torii, Masaaki
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.