Understanding and treating frontotemporal lobar degeneration (FTLD)
Project 2
This study is looking to better understand frontotemporal lobar degeneration (FTLD) and create new ways to track how the disease changes over time, so that patients can get the best treatments tailored to their specific needs.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project ID | NIH-10889909 on NIH RePORTER |
What this research studies
This research focuses on improving the understanding of frontotemporal lobar degeneration (FTLD) and developing new clinical tools to measure disease progression. It aims to create optimized clinical, imaging, and biomarker endpoints for clinical trials, allowing for better patient stratification based on their specific disease characteristics. By targeting the underlying biological mechanisms of FTLD, the research seeks to enhance the effectiveness of new therapies currently entering clinical trials. Patients will be monitored over time to assess changes in their condition and responses to treatments.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with frontotemporal lobar degeneration, particularly those with specific genetic or clinical variants.
Not a fit: Patients with other forms of dementia or neurological disorders unrelated to FTLD may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for patients with FTLD, improving their quality of life and potentially slowing disease progression.
How similar studies have performed: Previous research has shown promise in developing targeted therapies for FTLD, indicating that this approach could lead to significant advancements in treatment.
Where this research is happening
Rochester, United States
- Mayo Clinic Rochester — Rochester, United States (Active)
Researchers
- Principal investigator: Boxer, Adam L. — Mayo Clinic Rochester
- Study coordinator: Boxer, Adam L.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.