Understanding and Treating Fatty Liver Disease in Adults and Children
Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN)
This research network is working to find better ways to diagnose and treat a common liver condition called Metabolic Dysfunction Associated Steatotic Liver Disease (MASLD), also known as fatty liver disease, in both adults and children.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project ID | NIH-11166585 on NIH RePORTER |
What this research studies
Fatty liver disease has become the most common chronic liver condition, affecting both adults and children and potentially leading to serious complications like cirrhosis and liver cancer. Our team is part of a long-standing research network dedicated to turning scientific discoveries into practical solutions for patients. We aim to reduce how often this disease occurs, slow its progression, and improve health outcomes. This involves developing new diagnostic tests, identifying markers to track disease progression, and finding safe and effective treatments for MASLD.
Who could benefit from this research
Good fit: Patients with Metabolic Dysfunction Associated Steatotic Liver Disease (MASLD), including both adults and children, may be ideal candidates for future related studies.
Not a fit: Individuals who do not have Metabolic Dysfunction Associated Steatotic Liver Disease (MASLD) would not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to earlier diagnosis and more effective treatments for fatty liver disease, improving the health and quality of life for many patients.
How similar studies have performed: The NASH CRN has a successful track record over two decades, having established valuable databases, conducted randomized trials, and published high-quality research in this field.
Where this research is happening
Durham, United States
- Duke University — Durham, United States (Active)
Researchers
- Principal investigator: Diehl, Anna Mae Elizabeth — Duke University
- Study coordinator: Diehl, Anna Mae Elizabeth
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.