Understanding and treating fatty liver disease at the Cleveland Clinic
Continuation of the Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN) Clinical Center-Cleveland site
This network helps us learn more about fatty liver disease in adults and children and find better ways to treat it.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cleveland Clinic Lerner Com-Cwru NIH-funded |
| Lab location | 1 site (Cleveland, United States) |
| Project ID | NIH-11168964 on NIH RePORTER |
What this research studies
Our team at the Cleveland Clinic is part of a larger network dedicated to understanding non-alcoholic fatty liver disease (NAFLD), also known as metabolic dysfunction-associated steatotic liver disease (MASLD), and its more severe form, NASH (MASH). We are gathering information from adults and children with these conditions to better understand how they develop and progress. Our goal is to find new ways to diagnose these diseases without invasive procedures and to discover safe and effective treatments. This work includes completing ongoing studies and analyzing existing patient data.
Who could benefit from this research
Good fit: Ideal candidates for related studies would be adults and children diagnosed with non-alcoholic fatty liver disease (NAFLD) or non-alcoholic steatohepatitis (NASH).
Not a fit: Patients without a diagnosis of NAFLD or NASH would not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to new ways to diagnose fatty liver disease earlier and develop much-needed treatments for patients.
How similar studies have performed: While there are no currently licensed treatments for NASH, this network builds upon years of collaborative research to advance understanding and treatment development.
Where this research is happening
Cleveland, United States
- Cleveland Clinic Lerner Com-Cwru — Cleveland, United States (Active)
Researchers
- Principal investigator: Dasarathy, Srinivasan — Cleveland Clinic Lerner Com-Cwru
- Study coordinator: Dasarathy, Srinivasan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.