Understanding and Treating Fatty Liver Disease
Clinical Research on Nonalcoholic Fatty Liver Disease
This project aims to find better ways to understand, diagnose, and treat fatty liver disease, which affects many adults and children.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project ID | NIH-11166644 on NIH RePORTER |
What this research studies
Fatty liver disease, now called MASLD, affects a large number of adults and children in the United States. For some, it can progress to a more serious form called MASH, which can lead to liver damage and other severe health problems. Currently, there are no approved medicines specifically for MASH. This long-standing research network is working to find effective treatments and develop better ways to detect the disease and predict how it might progress.
Who could benefit from this research
Good fit: Individuals with metabolic dysfunction-associated steatotic liver disease (MASLD), also known as nonalcoholic fatty liver disease (NAFLD), including both adults and children, are the focus of this work.
Not a fit: Patients without MASLD or NAFLD would not directly benefit from this specific research.
Why it matters
Potential benefit: If successful, this work could lead to new medicines and improved diagnostic tools for individuals living with fatty liver disease.
How similar studies have performed: The NASH CRN has been actively working since 2002, successfully characterizing the natural history of MASLD and developing diagnostics, indicating a track record of progress in this area.
Where this research is happening
La Jolla, United States
- University of California, San Diego — La Jolla, United States (Active)
Researchers
- Principal investigator: Loomba, Rohit — University of California, San Diego
- Study coordinator: Loomba, Rohit
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.