Understanding and Treating Endometriosis
Epigenetic regulatory mechanisms and therapeutic opportunities in endometriosis
['FUNDING_R01'] · MICHIGAN STATE UNIVERSITY · NIH-11112412
This project aims to find new, non-hormonal ways to treat endometriosis by understanding how abnormal tissue grows.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | MICHIGAN STATE UNIVERSITY (nih funded) |
| Locations | 1 site (EAST LANSING, UNITED STATES) |
| Trial ID | NIH-11112412 on ClinicalTrials.gov |
What this research studies
Endometriosis affects many women, causing chronic pain and infertility, and current treatments are often limited to surgery or hormone therapy. We are looking for new treatments that specifically target the abnormal tissue without using hormones. Our approach involves exploring how changes in gene regulation, called epigenetics, might cause endometriosis to develop. By studying these changes, we hope to discover new ways to stop the disease from progressing.
Who could benefit from this research
Good fit: Patients with endometriosis who are seeking non-hormonal treatment options may benefit from the future therapies developed from this foundational research.
Not a fit: Patients whose endometriosis symptoms are well-managed by current hormonal therapies or surgery may not directly benefit from this specific research focus on new non-hormonal options.
Why it matters
Potential benefit: If successful, this work could lead to new, non-hormonal treatments that specifically target the abnormal tissue causing endometriosis.
How similar studies have performed: This work builds on recent discoveries about genetic mutations in endometriosis, suggesting a novel approach to understanding and treating the disease.
Where this research is happening
EAST LANSING, UNITED STATES
- MICHIGAN STATE UNIVERSITY — EAST LANSING, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: CHANDLER, RONALD L — MICHIGAN STATE UNIVERSITY
- Study coordinator: CHANDLER, RONALD L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.