Understanding and treating early signs of neurodegenerative diseases
NAPS2 Administrative Core
This study is looking at early signs of Parkinson's disease and related conditions, especially focusing on sleep behaviors that might signal a risk, and it's for anyone interested in helping researchers find better ways to understand and treat these diseases.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project ID | NIH-10866363 on NIH RePORTER |
What this research studies
This research focuses on synucleinopathies, which include conditions like Parkinson's disease and dementia with Lewy bodies, affecting millions of Americans. It aims to investigate the early signs of these diseases, particularly through the lens of Rapid Eye Movement Sleep Behavior Disorder (RBD), which may indicate a risk for developing these conditions. The study will involve collecting and analyzing biological samples and data from participants to identify potential biomarkers and track disease progression over time. By establishing a consortium of researchers and participants, the project seeks to enhance our understanding of these disorders and improve treatment strategies.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing symptoms of Rapid Eye Movement Sleep Behavior Disorder or those at risk for synucleinopathies.
Not a fit: Patients who do not exhibit any symptoms of sleep disorders or neurodegenerative diseases may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier interventions that may slow the progression of neurodegenerative diseases.
How similar studies have performed: Previous research has shown promise in identifying biomarkers for neurodegenerative diseases, suggesting that this approach could yield valuable insights.
Where this research is happening
Saint Louis, United States
- Washington University — Saint Louis, United States (Active)
Researchers
- Principal investigator: Ju, Yo-El S — Washington University
- Study coordinator: Ju, Yo-El S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.