Understanding and treating cystic fibrosis and its related complications
DartCF: The Dartmouth Cystic Fibrosis Research Center
This study is looking into how cystic fibrosis affects the body and how we can improve treatments, so people with CF can better manage their health and live healthier lives.
Quick facts
| Grant type | P30 center grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Dartmouth College NIH-funded |
| Lab location | 1 site (Hanover, United States) |
| Project ID | NIH-11115348 on NIH RePORTER |
What this research studies
This research focuses on cystic fibrosis (CF), a genetic disorder caused by mutations in the CFTR gene, leading to various health issues such as chronic lung infections and diabetes. The team at Dartmouth aims to explore the complex relationships between CFTR function, microbial interactions, and immune responses to improve treatment strategies. By fostering collaboration among 49 faculty members, the research seeks to develop new insights and therapies that address both the basic biology and clinical challenges of CF. Patients may benefit from advancements in understanding how to better manage their condition and its complications.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with cystic fibrosis, particularly those experiencing complications such as chronic infections or diabetes.
Not a fit: Patients with cystic fibrosis who are not experiencing significant complications or who have other unrelated health issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments and management strategies for cystic fibrosis patients, enhancing their quality of life.
How similar studies have performed: Previous research has shown promising results in understanding the role of CFTR modulators and microbial interactions in cystic fibrosis, indicating that this approach has potential for significant advancements.
Where this research is happening
Hanover, United States
- Dartmouth College — Hanover, United States (Active)
Researchers
- Principal investigator: Madden, Dean R — Dartmouth College
- Study coordinator: Madden, Dean R
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.