Understanding and treating cystic fibrosis and its related complications
DartCF: The Dartmouth Cystic Fibrosis Research Center
This study is looking at how cystic fibrosis affects the lungs and gut, and how these areas work with the immune system, to find new ways to help people with the condition feel better.
Quick facts
| Grant type | P30 center grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Dartmouth College NIH-funded |
| Lab location | 1 site (Hanover, United States) |
| Project ID | NIH-10914646 on NIH RePORTER |
What this research studies
This research focuses on cystic fibrosis (CF), a genetic disorder caused by mutations in the CFTR gene, leading to various health issues such as chronic lung infections and diabetes. The team at Dartmouth aims to explore the connections between CFTR function, gut and lung microbiomes, and the immune system to develop better treatment strategies. By fostering interdisciplinary collaboration among 49 faculty members, the research seeks to enhance our understanding of CF pathobiology and improve patient outcomes through innovative therapies.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with cystic fibrosis, particularly those experiencing complications related to lung infections or diabetes.
Not a fit: Patients without a diagnosis of cystic fibrosis or those with unrelated health conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for cystic fibrosis, improving the quality of life and health outcomes for patients.
How similar studies have performed: Previous research has shown promising results in understanding the microbiome's role in cystic fibrosis, indicating that this approach could lead to significant advancements in treatment.
Where this research is happening
Hanover, United States
- Dartmouth College — Hanover, United States (Active)
Researchers
- Principal investigator: Madden, Dean R — Dartmouth College
- Study coordinator: Madden, Dean R
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.