Understanding and treating brain metastases in cancer patients
TOOLKIT Core
This study is looking at how genes affect the spread of cancer to the brain, and it's for patients with brain metastases, as researchers are using new tools to find better ways to treat this condition.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project ID | NIH-10925249 on NIH RePORTER |
What this research studies
This research focuses on the genetic factors that contribute to brain metastases, which are a significant cause of cancer-related deaths. The Stanford Brain Metastasis Consortium is developing innovative models and tools, including 3D organoids and CRISPR technology, to better understand how tumors spread to the brain and how they interact with the immune system. By utilizing these advanced methodologies, the research aims to uncover new therapeutic strategies that could improve treatment outcomes for patients with brain metastases.
Who could benefit from this research
Good fit: Ideal candidates for this research include patients diagnosed with brain metastases from various primary cancers.
Not a fit: Patients with primary brain tumors that do not metastasize or those without any brain involvement may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to the development of more effective treatments for patients with brain metastases, potentially improving survival rates.
How similar studies have performed: Other research has shown promise in using CRISPR and organoid models to study cancer, indicating that this approach could yield valuable insights.
Where this research is happening
Stanford, United States
- Stanford University — Stanford, United States (Active)
Researchers
- Principal investigator: Kuo, Calvin J — Stanford University
- Study coordinator: Kuo, Calvin J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.