Understanding and treating autoimmune diseases through molecular insights
Oklahoma ACE: Molecular Destruction of Autoimmune Disease to Aid Clinical Trail Success
['FUNDING_OTHER'] · OKLAHOMA MEDICAL RESEARCH FOUNDATION · NIH-11082381
The Oklahoma ACE project is looking into how autoimmune diseases work, especially how the Epstein-Barr virus might affect them, and it’s testing new treatments like short-term steroid use and vaccines to help improve care for people with these conditions.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | OKLAHOMA MEDICAL RESEARCH FOUNDATION (nih funded) |
| Locations | 1 site (OKLAHOMA CITY, UNITED STATES) |
| Trial ID | NIH-11082381 on ClinicalTrials.gov |
What this research studies
The Oklahoma ACE project focuses on unraveling the complexities of autoimmune diseases by integrating clinical and basic research. It aims to explore the genetic and biological factors that contribute to these conditions, particularly looking at the role of Epstein-Barr virus (EBV) reactivation in disease activity. The research involves innovative clinical trial designs that include temporary steroid treatments and EBV vaccinations to assess their effects on disease management. By building diverse patient cohorts and utilizing advanced methodologies, the project seeks to enhance treatment strategies and improve patient outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with systemic lupus erythematosus (SLE) who are experiencing disease activity and may benefit from EBV vaccination.
Not a fit: Patients with autoimmune diseases other than SLE or those who are not experiencing active disease may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for autoimmune diseases, improving the quality of life for patients.
How similar studies have performed: Previous research has shown promising results in understanding the role of viral infections in autoimmune diseases, indicating that this approach has potential for success.
Where this research is happening
OKLAHOMA CITY, UNITED STATES
- OKLAHOMA MEDICAL RESEARCH FOUNDATION — OKLAHOMA CITY, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: JAMES, JUDITH A — OKLAHOMA MEDICAL RESEARCH FOUNDATION
- Study coordinator: JAMES, JUDITH A
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.