Understanding and treating atrial fibrillation using genetic insights
Network and Systems Biology Scientific Core 3
This study is looking at atrial fibrillation, a heart rhythm problem that can lead to strokes, to find new ways to prevent and treat it, using advanced techniques to better understand how it works, which could lead to safer and more effective options for patients like you.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cleveland Clinic Lerner Com-Cwru NIH-funded |
| Lab location | 1 site (Cleveland, United States) |
| Project ID | NIH-10896381 on NIH RePORTER |
What this research studies
This research focuses on atrial fibrillation (AF), a common heart rhythm disorder that increases the risk of stroke and cardiovascular issues. By analyzing genetic and molecular data, the project aims to identify new preventative and therapeutic strategies for AF. The research will utilize advanced techniques like RNA sequencing to gather insights into the biological mechanisms of AF, which will help in developing safer and more effective treatments. Patients may benefit from improved management options as the findings are translated into clinical applications.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with atrial fibrillation, particularly those affected by obesity or older age.
Not a fit: Patients without atrial fibrillation or those with other unrelated cardiovascular conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new and more effective treatments for atrial fibrillation, improving patient outcomes.
How similar studies have performed: Previous research has shown promise in using genomic approaches to understand and treat atrial fibrillation, indicating potential for success in this area.
Where this research is happening
Cleveland, United States
- Cleveland Clinic Lerner Com-Cwru — Cleveland, United States (Active)
Researchers
- Principal investigator: Barnard, John — Cleveland Clinic Lerner Com-Cwru
- Study coordinator: Barnard, John
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.